Machine Learning in Life Sciences Laboratory
University of A Coruña - CITIC
Hi!! We investigate omic data using machine learning to unveil patterns in complex diseases, identify biomarkers, and predict outcomes and drug responses, contributing to the advancement of understanding and personalization in life sciences research.
Research Lines
Bioinformatics
Our team, composed of biologists and bioinformaticians, leverages computational tools to extract meaningful biological insights from a variety of genomic datasets. Our research spans from plant genomics to the study of infectious bacterial diseases, aiming to unravel the molecular mechanisms underlying these biological systems.
Biomedical Data Science
We apply data science techniques to analyze omic datasets, with a particular focus on identifying diagnostic and predictive biomarkers in complex diseases. Our goal is to support personalized medicine approaches by uncovering patterns and associations that inform clinical decision-making.
Omic Integration
Our research focuses on the integration of multi-omic data (genomics, transcriptomics, proteomics, etc.) to understand molecular interactions across different biological layers. By combining diverse datasets, we aim to enhance our understanding of disease mechanisms and improve strategies for diagnosis and treatment.
news
| Oct 28, 2026 | New collaboration preprint on bioRxiv with the CellCOM group: Dual Role of Cx43 in Enhancing CDK4/6 Inhibitor Response and Promoting the Elimination of Therapy-Induced Senescent Tumor Cells |
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| Sep 30, 2026 | Paula Guijarro Sánchez successfully defended her PhD thesis “Desarrollo de metodologías bioinformáticas para el análisis genómico de la resistencia a antibióticos en Acinetobacter spp. y Klebsiella pneumoniae: estudios nacionales e implicaciones para la vigilancia activa en entornos hospitalarios”, earning the highest grade (Sobresaliente Cum Laude). Congratulations, Dr. Guijarro Sánchez! UDC thesis record |
| Sep 14, 2026 | New preprint on bioRxiv: Heterogeneous graph neural networks with biological prior knowledge for interpretable drug repurposing in triple-negative breast cancer |
| Aug 13, 2026 | New conference contribution at RExPO26 (REPO4EU Annual Conference): RePo-SUDOE – Advances on the transnational network for drug repurposing in the SUDOE space |
| Apr 17, 2026 | Raúl Mouzo Quiza has won the First Prize at the XI Premios TFG Aplicado del GEI for his work “Plataforma integrada para la simulación de docking molecular y el análisis de firmas genéticas en entornos HPC y cloud”. Congratulations! |
selected publications
- Heterogeneous graph neural networks with biological prior knowledge for interpretable drug repurposing in triple-negative breast cancerbioRxiv, 2026Preprint
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Interpretable inflammation landscape of circulating immune cellsNature Medicine, 2026Q1, D1, 1/1195 MR&E, 50 IF -
Cx43 enhances response to BRAF/MEK inhibitors by reducing DNA repair capacityNature Communications , 2025Q1, D1, 10/136 MS, 15.7 IF -
A review on machine learning approaches and trends in drug discoveryComputational and Structural Biotechnology Journal, Aug 2021Q1, 70/297 BIO-MB, 6.155 IF